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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1993-1-7
|
| pubmed:abstractText |
The significance of the BANS location (upper Back, posterior Arm, Neck and Scalp) as a prognostic factor in patients with stage I melanoma is controversial. A meta-analysis performed by Weinstock et al. on their own and five comparable studies corroborated the hypothesis that this location is influential in the prognosis of intermediate thickness (0.76-1.69 mm) melanomas. Our study investigated the relationship between BANS subsites, thickness and prognosis in 1,082 stage I melanoma patients from two major Italian centres, Turin and Florence. A BANS primary was observed in 212 (19.5%) patients: recurrences occurred in 85 of them (40.1%) vs 309/870 non-BANS patients (35.5%). Overall survival probabilities were significantly shorter (p less than 0.01) in the BANS group (69.1% vs 76.7% at 5 years; 59% vs 68.5% at 10 years). The prognostic value of the BANS location was confirmed by a multivariate analysis using the Cox proportional hazards model. Stratification of BANS and non-BANS groups by thickness clusters showed a significant difference in both survival (p less than 0.001) and disease-free interval (p less than 0.05) in the 3.01-4.00 mm thickness subset, due to the greater incidence of distant and visceral metastases. In the 0.76-1.69 mm thickness range the significance was p = 0.06.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0960-8931
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
157-62
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:1450669-Adolescent,
pubmed-meshheading:1450669-Adult,
pubmed-meshheading:1450669-Aged,
pubmed-meshheading:1450669-Aged, 80 and over,
pubmed-meshheading:1450669-Arm,
pubmed-meshheading:1450669-Back,
pubmed-meshheading:1450669-Female,
pubmed-meshheading:1450669-Head and Neck Neoplasms,
pubmed-meshheading:1450669-Humans,
pubmed-meshheading:1450669-Incidence,
pubmed-meshheading:1450669-Italy,
pubmed-meshheading:1450669-Life Tables,
pubmed-meshheading:1450669-Male,
pubmed-meshheading:1450669-Melanoma,
pubmed-meshheading:1450669-Middle Aged,
pubmed-meshheading:1450669-Neck,
pubmed-meshheading:1450669-Neoplasm Metastasis,
pubmed-meshheading:1450669-Neoplasm Recurrence, Local,
pubmed-meshheading:1450669-Prognosis,
pubmed-meshheading:1450669-Proportional Hazards Models,
pubmed-meshheading:1450669-Prospective Studies,
pubmed-meshheading:1450669-Scalp,
pubmed-meshheading:1450669-Skin Neoplasms,
pubmed-meshheading:1450669-Survival Analysis,
pubmed-meshheading:1450669-Survival Rate
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
BANS: a discussion of the problem.
|
| pubmed:affiliation |
Dermatological Clinic, University of Turin, Italy.
|
| pubmed:publicationType |
Journal Article
|