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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1993-1-6
|
| pubmed:abstractText |
Several pathways for reactive species formation involving xenobiotic metabolism exist in the brain. They include oxidative activation by different enzymatic systems like cytochrome P-450 and monoamine oxidases, and superoxide radical production issued from reductive xenobiotic metabolism. They may contribute to cellular impairment observed in various physiopathological situations.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1023-294X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
62
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
219-26
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1450587-Animals,
pubmed-meshheading:1450587-Blood-Brain Barrier,
pubmed-meshheading:1450587-Brain,
pubmed-meshheading:1450587-Catalase,
pubmed-meshheading:1450587-Cytochrome P-450 Enzyme System,
pubmed-meshheading:1450587-Oxidation-Reduction,
pubmed-meshheading:1450587-Oxidoreductases,
pubmed-meshheading:1450587-Pharmaceutical Preparations
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Evidence for drug metabolism as a source of reactive species in the brain.
|
| pubmed:affiliation |
Centre du Médicament, Université de Nancy I, CNRS URA 597, France.
|
| pubmed:publicationType |
Journal Article,
Review
|