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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1993-1-6
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pubmed:abstractText |
Serial studies of the plasma protein C-protein S system were performed during the clinical course of a pregnant woman with meningococcaemia who recovered under therapy. The patient had limited purpura fulminans skin lesions and hereditary C4b-binding protein deficiency was suspected. This diagnosis was confirmed in the patient 1 year after delivery and also by family studies. During the meningococcaemia, an initial mild and transient acquired protein C deficiency was seen but no protein S deficiency was observed despite consumption of the latter protein. As C4b-binding protein partial deficiency is associated with high free protein S and protein S activity, this may have protected against acquired protein S deficiency during meningococcaemia.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0957-5235
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
3
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
673-7
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:1450338-Adult,
pubmed-meshheading:1450338-Carrier Proteins,
pubmed-meshheading:1450338-Child,
pubmed-meshheading:1450338-Complement Inactivator Proteins,
pubmed-meshheading:1450338-Female,
pubmed-meshheading:1450338-Glycoproteins,
pubmed-meshheading:1450338-Humans,
pubmed-meshheading:1450338-Male,
pubmed-meshheading:1450338-Meningitis, Meningococcal,
pubmed-meshheading:1450338-Pregnancy,
pubmed-meshheading:1450338-Pregnancy Complications, Infectious,
pubmed-meshheading:1450338-Protein S,
pubmed-meshheading:1450338-Purpura
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pubmed:year |
1992
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pubmed:articleTitle |
Meningococcaemia in an adult with hereditary C4b-binding protein deficiency: study of the variations of the protein S system.
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pubmed:affiliation |
Laboratoire d'Hématologie et Immunologie, CHU, Nîmes, France.
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pubmed:publicationType |
Journal Article,
Case Reports
|