Source:http://linkedlifedata.com/resource/pubmed/id/14502271
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2003-9-22
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pubmed:abstractText |
For more than a quarter of a century, macrophage migration inhibitory factor (MIF) has been a mysterious cytokine. In recent years, MIF has assumed an important role as a pivotal regulator of innate immunity. MIF is an integral component of the host antimicrobial alarm system and stress response that promotes the pro-inflammatory functions of immune cells. A rapidly increasing amount of literature indicates that MIF is implicated in the pathogenesis of sepsis, and inflammatory and autoimmune diseases, suggesting that MIF-directed therapies might offer new treatment opportunities for human diseases in the future.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1474-1733
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
791-800
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:14502271-Animals,
pubmed-meshheading:14502271-Autoimmune Diseases,
pubmed-meshheading:14502271-Humans,
pubmed-meshheading:14502271-Immunity, Innate,
pubmed-meshheading:14502271-Inflammation,
pubmed-meshheading:14502271-Macrophage Migration-Inhibitory Factors,
pubmed-meshheading:14502271-Macrophages,
pubmed-meshheading:14502271-Sepsis
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pubmed:year |
2003
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pubmed:articleTitle |
Macrophage migration inhibitory factor: a regulator of innate immunity.
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pubmed:affiliation |
Division of Infectious Diseases, Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, CH-1011 Lausanne, Switzerland. Thierry.Calandra@hospvd.ch
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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