Linked Life Data

14501049

Source:http://linkedlifedata.com/resource/pubmed/id/14501049

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2003-9-22
pubmed:abstractText
RNA suppression approaches provide a rapid survey of gene function. Of these approaches (i.e., antisense oligonucleotides, ribozymes, and RNA interference), ribozymes offer significant advantages by operating as stringent site-specific ribonucleases. The purpose of this chapter is to provide some guidelines and protocols for the use of ribozymes to identify the functions of closely related members of the G protein gamma subunit family. Improvements in their design and delivery will be discussed, including the use of "second generation" ribozymes targeted against multiple cleavage sites.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1064-3745
pubmed:author
pubmed:issnType
Print
pubmed:volume
237
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
169-80
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Ribozymes as tools for suppression of G protein gamma subunits.
pubmed:affiliation
Weis Center for Research, Geisinger Clinic, Danville, PA, USA.
pubmed:publicationType
Journal Article, Review