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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2003-9-22
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pubmed:abstractText |
Lupus anticoagulant (LA) screens are frequently ordered in the workup of thrombophilic patients or women with fetal loss. The sensitivity and specificity of LA detection vary depending on the choice of tests, cutoff values, and results interpretation. This variation is detrimental to patient management because persistent LA positivity in patients with a history of thrombosis is a requisite for long-term anticoagulation therapy. Numerous surveys have been performed to assess the state of the art for LA diagnosis. The control plasmas used in these surveys were from LA-positive or -negative patients or were normal plasmas with monoclonal antibodies against human beta(2)-glycoprotein I (beta(2)-GPI) added.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0009-9147
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1608-14
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14500585-Antibodies, Monoclonal,
pubmed-meshheading:14500585-Chromatography, Affinity,
pubmed-meshheading:14500585-Cross Reactions,
pubmed-meshheading:14500585-Data Collection,
pubmed-meshheading:14500585-Glycoproteins,
pubmed-meshheading:14500585-Humans,
pubmed-meshheading:14500585-Immunoassay,
pubmed-meshheading:14500585-Immunoglobulin G,
pubmed-meshheading:14500585-Italy,
pubmed-meshheading:14500585-Laboratories, Hospital,
pubmed-meshheading:14500585-Lupus Coagulation Inhibitor,
pubmed-meshheading:14500585-Sensitivity and Specificity,
pubmed-meshheading:14500585-Thrombophilia,
pubmed-meshheading:14500585-beta 2-Glycoprotein I
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pubmed:year |
2003
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pubmed:articleTitle |
Lupus anticoagulant (LA) testing: performance of clinical laboratories assessed by a national survey using lyophilized affinity-purified immunoglobulin with LA activity.
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pubmed:affiliation |
Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Internal Medicine, University and IRCCS Maggiore Hospital, 20122 Milan, Italy. armando.tripodi@unimi.it
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pubmed:publicationType |
Journal Article
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