Source:http://linkedlifedata.com/resource/pubmed/id/14500110
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2003-9-22
|
| pubmed:abstractText |
We used a psychophysiological marker of visual attention (the visual scanpath) to investigate the effects of atypical (risperidone) vs. typical (haloperidol) antipsychotic medication on facial emotion perception in schizophrenia (n=28) and healthy control (n=28) groups. Of the schizophrenia subjects, 15 were prescribed risperidone. Visual scanpaths to 'happy', 'sad' and 'neutral' faces were recorded using video-oculography, and concurrent emotion-recognition accuracy was assessed using multiple-option tasks. Compared to control subjects, both schizophrenia subgroups showed a restriction in visual scanning (reduced total fixation number and decreased scanpath length). Haloperidol-treated schizophrenia subjects exhibited an additional and consistent pattern of reduced attention (fixation) to salient features for neutral and happy. By contrast, risperidone-treated subjects showed a relatively greater attention to salient features for these expressions, in which they did not differ from controls. Recognition accuracy for happy and neutral showed a similar lack of impairment. These findings suggest that risperidone may play a specific role in schizophrenia in the ability to attend to salient features, and to integrate this information into an accurate percept for neutral and positive expressions in particular.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0165-1781
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
30
|
| pubmed:volume |
120
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
13-27
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| pubmed:dateRevised |
2008-4-17
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| pubmed:meshHeading |
pubmed-meshheading:14500110-Adult,
pubmed-meshheading:14500110-Antipsychotic Agents,
pubmed-meshheading:14500110-Attention,
pubmed-meshheading:14500110-Chronic Disease,
pubmed-meshheading:14500110-Emotions,
pubmed-meshheading:14500110-Eye Movements,
pubmed-meshheading:14500110-Facial Expression,
pubmed-meshheading:14500110-Female,
pubmed-meshheading:14500110-Fixation, Ocular,
pubmed-meshheading:14500110-Haloperidol,
pubmed-meshheading:14500110-Humans,
pubmed-meshheading:14500110-Male,
pubmed-meshheading:14500110-Middle Aged,
pubmed-meshheading:14500110-Pattern Recognition, Visual,
pubmed-meshheading:14500110-Psychiatric Status Rating Scales,
pubmed-meshheading:14500110-Risperidone,
pubmed-meshheading:14500110-Schizophrenia,
pubmed-meshheading:14500110-Schizophrenic Psychology,
pubmed-meshheading:14500110-Social Perception
|
| pubmed:year |
2003
|
| pubmed:articleTitle |
Emotion perception in schizophrenia: an eye movement study comparing the effectiveness of risperidone vs. haloperidol.
|
| pubmed:affiliation |
School of Psychology, University of Sydney, Sydney, NSW 2006, Australia. lea@psych.usyd.edu.au
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
|