Linked Life Data

14499155

Source:http://linkedlifedata.com/resource/pubmed/id/14499155

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2003-9-22
pubmed:abstractText
In multicellular organisms, homeostasis is maintained by a balance between cell proliferation and apoptosis (programmed cell death). It is a physiological form of cell death responsible for the deletion of not reparable damaged, mutated, or cells which have lost their function. Apoptosis can be distinguished by morphological and biochemical characteristics from necrosis (pathological cell death). Apoptotic cell death does not disturb surrounding cells. To achieve the elimination of cells without an inflammatory reaction, a complex interplay of several molecules is necessary. Apoptosis either starts from the cell surface (CD95-CD95L), the mitochondrion or from the nucleus. The cell biological events run in a cascaded fashion and are regulated by either enhancer or anti-apoptotic signals that probably may stop the executions machinery. The knowledge about apoptosis helps to understand pathophysiologic conditions, to better diagnose and treat them by molecular radiological techniques.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1536-1632
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2-14
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Apoptosis: the complex scenario for a silent cell death.
pubmed:affiliation
Department of Radiology, Rheinische Friedrich-Wilhelms, University of Bonn, Bonn, Germany. i.boehm@uni-bonn.de
pubmed:publicationType
Journal Article, Review