Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
18
|
| pubmed:dateCreated |
1992-12-18
|
| pubmed:abstractText |
The epidemiology, clinical features, microbiology and outcome of 30 episodes of nosocomial endocarditis occurring over a 13-year period were reviewed and compared with 148 cases of community-acquired endocarditis. Twenty-eight patients (93%) had been in hospital for > 1 week and 10 patients (33%) for > 1 month when they developed endocarditis. Left-sided infection was most frequent; only 3 cases involved the tricuspid valve. Compared with community-acquired infection, patients tended to be older, had a greater incidence of congestive cardiac failure (p = 0.001) or hypotension (p = 0.0008) at presentation and were more likely to have bacteremia after an invasive procedure (83 vs 31%; p < 0.00001). Intravascular devices were the presumed source of bacteremia in 11 cases (37%); the same organism was isolated from both the blood and the suspected source of infection. Staphylococcus aureus was the most frequent causative organism, accounting for 17 episodes (57%), including 4 (13%) due to methicillin-resistant strains. Nosocomial endocarditis had a significantly higher mortality than did community-acquired infection (40 vs 18%; p = 0.02). Eight patients (27%) needed valve replacement. Proper adherence to protocols for management of intravascular devices and appropriate antimicrobial prophylaxis before procedures may have prevented endocarditis in 15 of 30 patients.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0002-9149
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
70
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1449-52
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1442617-Adult,
pubmed-meshheading:1442617-Age Factors,
pubmed-meshheading:1442617-Aged,
pubmed-meshheading:1442617-Bacteremia,
pubmed-meshheading:1442617-Catheterization, Peripheral,
pubmed-meshheading:1442617-Cross Infection,
pubmed-meshheading:1442617-Endocarditis, Bacterial,
pubmed-meshheading:1442617-Female,
pubmed-meshheading:1442617-Fever,
pubmed-meshheading:1442617-Heart Failure,
pubmed-meshheading:1442617-Heart Valve Diseases,
pubmed-meshheading:1442617-Heart Valve Prosthesis,
pubmed-meshheading:1442617-Humans,
pubmed-meshheading:1442617-Hypotension,
pubmed-meshheading:1442617-Incidence,
pubmed-meshheading:1442617-Length of Stay,
pubmed-meshheading:1442617-Male,
pubmed-meshheading:1442617-Middle Aged,
pubmed-meshheading:1442617-New South Wales,
pubmed-meshheading:1442617-Prognosis,
pubmed-meshheading:1442617-Staphylococcal Infections,
pubmed-meshheading:1442617-Survival Rate
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
A comparison of hospital and community-acquired infective endocarditis.
|
| pubmed:affiliation |
Centre for Infectious Diseases and Microbiology, University of Sydney, Westmead Hospital, New South Wales, Australia.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|