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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1992-12-16
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pubmed:abstractText |
Disorders in vestibulo-ocular functions were studied in 4 patients with olivo-ponto-cerebellar atrophy (OPCA). The phenomenon of habituation, considered as a plastic property of the vestibulo-ocular reflex (VOR), was explored with a behavioural paradigm in these patients. When subjected to the habituation paradigm all patients presented a modified response opposite to that observed in normal subjects. The role played by the cerebellum in relation to VOR plasticity--well known in different experimental models--is analyzed. The hypothesis of a modification of the cerebellum's inhibitory action on vestibular nuclei neurons is put forward to explain the inversion of the VOR habituation phenomenon in these patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0001-6489
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
112
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
589-94
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1442002-Adult,
pubmed-meshheading:1442002-Case-Control Studies,
pubmed-meshheading:1442002-Cerebellum,
pubmed-meshheading:1442002-Female,
pubmed-meshheading:1442002-Habituation, Psychophysiologic,
pubmed-meshheading:1442002-Humans,
pubmed-meshheading:1442002-Male,
pubmed-meshheading:1442002-Middle Aged,
pubmed-meshheading:1442002-Neuronal Plasticity,
pubmed-meshheading:1442002-Olivopontocerebellar Atrophies,
pubmed-meshheading:1442002-Reflex, Vestibulo-Ocular,
pubmed-meshheading:1442002-Vestibular Nuclei
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pubmed:year |
1992
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pubmed:articleTitle |
Plastic properties of the vestibulo-ocular reflex in olivo-ponto-cerebellar atrophy.
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pubmed:affiliation |
Laboratorio de Fisiopatologia Vestibular de Medicina, Montevideo, Uruguay.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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