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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
1992-12-4
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pubmed:abstractText |
Two multicopy suppressors of the cal1-1 mutation in the yeast Saccharomyces cerevisiae have been isolated and characterized. They are identical to the yeast RHO1 and RHO2 genes, which encode putative small GTP-binding proteins. Multiple copies of either RHO gene suppressed temperature-sensitive growth of the cal1-1 mutant but did not suppress the cal1 null mutant. Genetic analysis suggests that overproduction of either RHO gene product acts for activation of the CAL1 gene product.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alkyl and Aryl Transferases,
http://linkedlifedata.com/resource/pubmed/chemical/CDC43 protein, S cerevisiae,
http://linkedlifedata.com/resource/pubmed/chemical/CHS3 protein, S cerevisiae,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Chitin Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Fungal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/GTP-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Saccharomyces cerevisiae Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Transferases,
http://linkedlifedata.com/resource/pubmed/chemical/geranylgeranyltransferase type-I,
http://linkedlifedata.com/resource/pubmed/chemical/rhoB GTP-Binding Protein
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0749-503X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:geneSymbol |
CAL1,
CDC42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
735-41
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1441750-Alkyl and Aryl Transferases,
pubmed-meshheading:1441750-Cell Cycle Proteins,
pubmed-meshheading:1441750-Chitin Synthase,
pubmed-meshheading:1441750-Enzyme Activation,
pubmed-meshheading:1441750-Fungal Proteins,
pubmed-meshheading:1441750-GTP-Binding Proteins,
pubmed-meshheading:1441750-Genes, Fungal,
pubmed-meshheading:1441750-Genes, Suppressor,
pubmed-meshheading:1441750-Membrane Proteins,
pubmed-meshheading:1441750-Mutation,
pubmed-meshheading:1441750-Saccharomyces cerevisiae,
pubmed-meshheading:1441750-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:1441750-Transferases,
pubmed-meshheading:1441750-rhoB GTP-Binding Protein
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pubmed:year |
1992
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pubmed:articleTitle |
RHO gene products, putative small GTP-binding proteins, are important for activation of the CAL1/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae.
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pubmed:affiliation |
Department of Biology, Faculty of Science, University of Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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