rdf:type |
|
lifeskim:mentions |
umls-concept:C0006104,
umls-concept:C0030685,
umls-concept:C0034693,
umls-concept:C0127400,
umls-concept:C0232105,
umls-concept:C0391871,
umls-concept:C0425710,
umls-concept:C0680255,
umls-concept:C0857121,
umls-concept:C1283071,
umls-concept:C1363844,
umls-concept:C1963578
|
pubmed:issue |
11
|
pubmed:dateCreated |
1992-12-1
|
pubmed:abstractText |
We reported previously that stroke risk factors prepared the brain stem for the development of ischemia and hemorrhage and induced the production of tumor necrosis factor following an intrathecal injection of lipopolysaccharide, a prototypic monocyte-activating stimulus. This study evaluates whether blood or brain cells of hypertensive rats produce more proinflammatory and prothrombotic mediators than do blood or brain cells of normotensive rats.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0039-2499
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1643-50; discussion 1650-1
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:1440713-Animals,
pubmed-meshheading:1440713-Brain,
pubmed-meshheading:1440713-Cerebrovascular Disorders,
pubmed-meshheading:1440713-Dose-Response Relationship, Drug,
pubmed-meshheading:1440713-Hypertension,
pubmed-meshheading:1440713-Injections, Intravenous,
pubmed-meshheading:1440713-Injections, Intraventricular,
pubmed-meshheading:1440713-Leukocyte Count,
pubmed-meshheading:1440713-Lipopolysaccharides,
pubmed-meshheading:1440713-Platelet Activating Factor,
pubmed-meshheading:1440713-Rats,
pubmed-meshheading:1440713-Rats, Inbred SHR,
pubmed-meshheading:1440713-Rats, Inbred WKY,
pubmed-meshheading:1440713-Reference Values,
pubmed-meshheading:1440713-Risk Factors,
pubmed-meshheading:1440713-Thromboxane B2,
pubmed-meshheading:1440713-Tumor Necrosis Factor-alpha
|
pubmed:year |
1992
|
pubmed:articleTitle |
Release of proinflammatory and prothrombotic mediators in the brain and peripheral circulation in spontaneously hypertensive and normotensive Wistar-Kyoto rats.
|
pubmed:affiliation |
Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|