Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1992-12-15
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pubmed:abstractText |
In a two-year prospective therapeutic trial 13 patients with systemic sclerosis (SSc) were treated with penicillamine, 9 with cyclofenil, and 7 with neither. At entry skin involvement and esophageal, lung, heart, and kidney function did not differ significantly between the groups. Reevaluation after one and two years did not show any significant changes in skin, esophageal, heart, and kidney manifestations, while lung function had slightly improved in both drug-treatment groups. This study thus shows little overall effect of penicillamine and cyclofenil, although both drugs may arrest worsening of pulmonary dysfunction.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-9742
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
238-44
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1439632-Adult,
pubmed-meshheading:1439632-Aged,
pubmed-meshheading:1439632-Cyclofenil,
pubmed-meshheading:1439632-Electrocardiography,
pubmed-meshheading:1439632-Esophagus,
pubmed-meshheading:1439632-Exercise,
pubmed-meshheading:1439632-Female,
pubmed-meshheading:1439632-Heart,
pubmed-meshheading:1439632-Humans,
pubmed-meshheading:1439632-Immune System,
pubmed-meshheading:1439632-Kidney,
pubmed-meshheading:1439632-Lung,
pubmed-meshheading:1439632-Male,
pubmed-meshheading:1439632-Middle Aged,
pubmed-meshheading:1439632-Penicillamine,
pubmed-meshheading:1439632-Prospective Studies,
pubmed-meshheading:1439632-Scleroderma, Systemic,
pubmed-meshheading:1439632-Skin,
pubmed-meshheading:1439632-Time Factors,
pubmed-meshheading:1439632-Ventilation-Perfusion Ratio
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pubmed:year |
1992
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pubmed:articleTitle |
Long-term evaluation of penicillamine or cyclofenil in systemic sclerosis. Results from a two-year randomized study.
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pubmed:affiliation |
Department of Rheumatology, University Hospital, Lund, Sweden.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|