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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
4
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pubmed:dateCreated |
1992-12-4
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pubmed:abstractText |
The M protein gene (emm gene) from a reference group A streptococcal strain of serotype M3 was amplified by the polymerase chain reaction and partially sequenced. Hybridization assays using an oligonucleotide probe derived from the N-terminal sequence revealed that this gene segment is highly homologous among M-type 3 isolates. Of note, analysis of the nucleotide sequence data from the C terminus of the gene confirmed that the emm 3 gene exhibited all the features characteristic for group A streptococcal M-class I molecules. Recently published sequence data that were assigned to emm 3 resulted from a strain confusion and were shown to be the first one derived from an emm gene of an M-untypable isolate.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
0300-8584
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
181
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pubmed:geneSymbol |
emm 3
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|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
209-13
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|
pubmed:dateRevised |
2007-2-21
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pubmed:meshHeading |
pubmed-meshheading:1435517-Amino Acid Sequence,
pubmed-meshheading:1435517-Antigens, Bacterial,
pubmed-meshheading:1435517-Bacterial Outer Membrane Proteins,
pubmed-meshheading:1435517-Bacterial Proteins,
pubmed-meshheading:1435517-Base Sequence,
pubmed-meshheading:1435517-Carrier Proteins,
pubmed-meshheading:1435517-DNA, Bacterial,
pubmed-meshheading:1435517-Genes, Bacterial,
pubmed-meshheading:1435517-Molecular Sequence Data,
pubmed-meshheading:1435517-Polymerase Chain Reaction,
pubmed-meshheading:1435517-Sequence Alignment,
pubmed-meshheading:1435517-Streptococcus pyogenes
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pubmed:year |
1992
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|
pubmed:articleTitle |
The group A streptococcal M-type 3 protein gene exhibits a C terminus typical for class I M proteins.
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pubmed:affiliation |
Institute of Medical Microbiology, Technical University (RWTH), Aachen, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study
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