Linked Life Data

1434919

Source:http://linkedlifedata.com/resource/pubmed/id/1434919

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1992-12-10
pubmed:abstractText
Complete and partial hydatidiform moles are genetically aberrant conceptuses. Usually, complete moles have 46 chromosomes (diploidy), all of paternal origin. Most partial moles have 69 chromosomes (triploidy), including 23 of maternal origin and 46 of paternal origin. Triploidy that involves 23 paternal chromosomes and 46 maternal chromosomes is not associated with molar placental changes and, rarely, can result in a live-born infant with multiple birth defects. Herein we review the mechanisms of fertilization that may produce these unbalanced sets of parental chromosomes and the role of genomic imprinting as a possible explanation for these clinical conditions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0025-6196
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
791-9
pubmed:dateRevised
2007-10-29
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
A genetic review of complete and partial hydatidiform moles and nonmolar triploidy.
pubmed:affiliation
Department of Medical Genetics, Mayo Clinic, Rochester, MN 55905.
pubmed:publicationType
Journal Article, Review