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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1965-12-1
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pubmed:abstractText |
1. Whole scrapings of rat intestinal mucosa were incubated with carrier-free sodium [(35)S]sulphate. Radioactivity was found in S-sulphocysteine and to a small extent in S-sulphoglutathione. 2. Whole scrapings of rat intestinal mucosa incubated with carrier-free sodium [(35)S]sulphate and oxidized glutathione formed S[(35)S]-sulphoglutathione as the main radioactive product. The amount of S[(35)S]-sulphocysteine formed was considerably lower than in a control that contained no oxidized glutathione. 3. The supernatant fraction of homogenates of rat intestinal mucosa catalyses the NADPH-dependent reduction of adenosine 3'-phosphate 5'-sulphatophosphate to inorganic sulphite. NADH or GSH fail to replace NADPH as reducing agents. 4. The formation of inorganic [(35)S]sulphite from inorganic [(35)S]-sulphate may account for the incorporation of [(35)S]sulphate into S-sulphoglutathione by the small intestine of the rat in vivo and in vitro.
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pubmed:commentsCorrections |
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pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/CHROMATOGRAPHY,
http://linkedlifedata.com/resource/pubmed/keyword/CYSTEINE,
http://linkedlifedata.com/resource/pubmed/keyword/EXPERIMENTAL LAB STUDY,
http://linkedlifedata.com/resource/pubmed/keyword/GLUTATHIONE,
http://linkedlifedata.com/resource/pubmed/keyword/HOMOGENATES,
http://linkedlifedata.com/resource/pubmed/keyword/INTESTINAL MUCOSA,
http://linkedlifedata.com/resource/pubmed/keyword/INTESTINE, SMALL,
http://linkedlifedata.com/resource/pubmed/keyword/METABOLISM,
http://linkedlifedata.com/resource/pubmed/keyword/NADP,
http://linkedlifedata.com/resource/pubmed/keyword/NUCLEOTIDYLTRANSFERASES,
http://linkedlifedata.com/resource/pubmed/keyword/PHOSPHOTRANSFERASES,
http://linkedlifedata.com/resource/pubmed/keyword/RATS,
http://linkedlifedata.com/resource/pubmed/keyword/SULFATES,
http://linkedlifedata.com/resource/pubmed/keyword/SULFITES
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
OM
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pubmed:chemical |
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pubmed:status |
OLDMEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0264-6021
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
687-91
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:14340059-Chromatography,
pubmed-meshheading:14340059-Cysteine,
pubmed-meshheading:14340059-Glutathione,
pubmed-meshheading:14340059-Intestinal Mucosa,
pubmed-meshheading:14340059-Intestine, Small,
pubmed-meshheading:14340059-Metabolism,
pubmed-meshheading:14340059-NADP,
pubmed-meshheading:14340059-Nucleotidyltransferases,
pubmed-meshheading:14340059-Phosphotransferases,
pubmed-meshheading:14340059-Rats,
pubmed-meshheading:14340059-Research,
pubmed-meshheading:14340059-Sulfates,
pubmed-meshheading:14340059-Sulfites
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pubmed:year |
1965
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pubmed:articleTitle |
THE REDUCTION OF INORGANIC SULPHATE TO INORGANIC SULPHITE IN THE SMALL INTESTINE OF THE RAT.
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pubmed:publicationType |
Journal Article
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