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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1977-4-30
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pubmed:abstractText |
This review describes some of the characteristics for renin's substrate specificity and also some features of its species specificity. It describes how competitive inhibitors were synthesized and how the solubility was increased in order to make them effective at physiological pH. Their use for in vitro and in vivo inhibition of renin is discussed and their use for purification of renin demonstrated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0079-6085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
135-41
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:14338-Animals,
pubmed-meshheading:14338-Binding, Competitive,
pubmed-meshheading:14338-Blood Pressure,
pubmed-meshheading:14338-Chemical Phenomena,
pubmed-meshheading:14338-Chemistry,
pubmed-meshheading:14338-Humans,
pubmed-meshheading:14338-Hydrogen-Ion Concentration,
pubmed-meshheading:14338-Kinetics,
pubmed-meshheading:14338-Oligopeptides,
pubmed-meshheading:14338-Peptides,
pubmed-meshheading:14338-Rats,
pubmed-meshheading:14338-Renin,
pubmed-meshheading:14338-Solubility,
pubmed-meshheading:14338-Species Specificity,
pubmed-meshheading:14338-Structure-Activity Relationship,
pubmed-meshheading:14338-Swine
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pubmed:year |
1976
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pubmed:articleTitle |
Competitive inhibitors of renin. A review.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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