Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1992-12-23
|
pubmed:abstractText |
Uveitis is a manifestation of various chronic inflammatory arthritic conditions. There are considerable data implicating abnormalities of immune function in the etiopathogenesis of uveitis. We evaluated the percentage of cells expressing interleukin 2 (IL-2) receptor (membrane bound) and the levels of soluble IL-2 in the blood and aqueous humor of patients in various rheumatic diseases and acute untreated uveitis. Our findings showed increased IL-2 receptors (IL-2R) and soluble IL-2 receptors on the aqueous humor of patients with uveitis when compared to healthy controls. These results suggest an immunoregulatory role of IL-2R in acute uveitis and raises the possibility that its detection may be useful in management.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0315-162X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1362-3
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1433001-Aqueous Humor,
pubmed-meshheading:1433001-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1433001-Fluorescent Antibody Technique,
pubmed-meshheading:1433001-Humans,
pubmed-meshheading:1433001-Receptors, Interleukin-2,
pubmed-meshheading:1433001-Solubility,
pubmed-meshheading:1433001-T-Lymphocytes,
pubmed-meshheading:1433001-Uveitis
|
pubmed:year |
1992
|
pubmed:articleTitle |
Interleukin 2 receptor membrane bound and in soluble form in the aqueous humor and peripheral blood of patients with acute untreated uveitis.
|
pubmed:affiliation |
Department of Rheumatology/Immunology, Cancer Institute Arnaldo Vieira de Carvalho, São Paulo, Brazil.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|