Linked Life Data

14278004

Source:http://linkedlifedata.com/resource/pubmed/id/14278004

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1965-7-1
pubmed:abstractText
A susceptible and a resistant strain were isolated from an originally heterogeneous laboratory colony of Culex quinquefasciatus Say (= Culex pipiens fatigans Wiedemann) by use of discriminating concentrations of dieldrin on fourth-instar larvae. By cross-breeding, hybrids of intermediate susceptibility were obtained. By repeated cross-breeding and elimination of susceptibles the authors have shown that resistance to dieldrin is controlled by a single inheritable factor which is neither fully recessive nor dominant in the hybrid genotype, since the ratios of the LC(50) values were 1:19:196. Cross-resistance was shown to lindane but not to malathion or to any of three carbamates.Similar tests were made with adult females exposed to papers impregnated with n-dioctyl phthalate as solvent to secure high concentrations of dieldrin. Resistance in this stage also was neither fully recessive nor dominant, but it can be calculated quantitatively only for the hydrid (approximately 15-fold) since longer exposure was required with the resistant genotype. Determination of dieldrin pick-up showed that this cannot account for the differences in susceptibility of the genotypes. Analysis of resistant females surviving exposure to dieldrin papers showed slow loss of dieldrin and thus added confirmation to the hypothesis that metabolism is not the controlling process in dieldrin-resistance.
pubmed:commentsCorrections
pubmed:keyword
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
OM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0042-9686
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
669-77
pubmed:dateRevised
2011-9-28
pubmed:meshHeading
pubmed:year
1964
pubmed:articleTitle
THE MONOFACTORIAL INHERITANCE OF RESISTANCE TO DIELDRIN IN LARVAL AND ADULT CULEX QUINQUEFASCIATUS SAY.
pubmed:publicationType
Journal Article