Linked Life Data

14267746

Source:http://linkedlifedata.com/resource/pubmed/id/14267746

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1965-6-1
pubmed:abstractText
Present methods for assessment of the attack phase of malaria eradication are inadequate, particularly lacking any objective parasitological criteria of success. On the basis of previous observations and development of theory, the authors first postulate that the effects of complete interruption of transmission should, ideally, include a regular progressive decrease of falciparum parasite rates in the ratios of 1: 0.4 in 6 months, 1: 0.16 in 12 months and 1: 0.026 in 24 months. Analysis of a series of programmes in which complete interruption of transmission is known to have been achieved shows that this postulate is valid, and that it is not materially upset by strain differences of parasites or by differences in the ages of the subjects examined. Vivax rates appear to fall at approximately the same rate; the rarity of data for vivax malaria makes firm conclusions unsure, but the postulate can be extended to rates which are predominantly due to falciparum infection but include some admixture of other species. A second, arbitrary, postulate is made that the slowest acceptable rate of fall in 12 months should be in a ratio not less than 1: 0.22, which would secure ultimate eradication in about one-third more time than the ideal fall; on this basis statistical standards are set up for assurance of confidence that the minimum rate is exceeded. Slower rates of fall are then related to reproduction rates causing them, the findings being illustrated graphically and by mathematical theory.
pubmed:commentsCorrections
pubmed:keyword
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
OM
pubmed:status
OLDMEDLINE
pubmed:issn
0042-9686
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
365-77
pubmed:dateRevised
2010-10-26
pubmed:meshHeading
pubmed:year
1964
pubmed:articleTitle
THE MALARIA PARASITE RATE AND INTERRUPTION OF TRANSMISSION.
pubmed:publicationType
Journal Article