| pubmed-article:1425933 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1425933 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:1425933 | lifeskim:mentions | umls-concept:C0040162 | lld:lifeskim |
| pubmed-article:1425933 | lifeskim:mentions | umls-concept:C0680727 | lld:lifeskim |
| pubmed-article:1425933 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
| pubmed-article:1425933 | lifeskim:mentions | umls-concept:C0232572 | lld:lifeskim |
| pubmed-article:1425933 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:1425933 | pubmed:issue | 2-3 | lld:pubmed |
| pubmed-article:1425933 | pubmed:dateCreated | 1992-12-4 | lld:pubmed |
| pubmed-article:1425933 | pubmed:abstractText | Centrally administered thyrotropin-releasing hormone (TRH) induces vagally mediated gastrointestinal effects which may be cholinergic, serotonergic or a combination. This study investigated mediation of TRH-stimulated gastric motility in developing rats. A serotonin (5-HT) antagonist (5-HT2, ketanserin or xylamidine; 5-HT3, MDL 72222) or an acetylcholine receptor blocker (atropine) was administered intraperitoneally 30 min prior to intracisternal TRH (5-10 micrograms). The 5-HT-depleting para-chlorophenylalanine (p-CPA) was administered 48 or 72 h prior to TRH. Gastric motility, monitored via extraluminal strain gauge, was not increased with TRH in atropine-pretreated rats. MDL 72222 had a significant age-related effect on TRH-induced gastric motility increases while 5-HT2 antagonists and p-CPA treatment did not. Thus, acetylcholine receptor blockade inhibits TRH-stimulated gastric motility in young and adult rats while 5-HT3 antagonism eliminates the motility response in young (7 and 10 days) rats. | lld:pubmed |
| pubmed-article:1425933 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1425933 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1425933 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1425933 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1425933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1425933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1425933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1425933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1425933 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1425933 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:1425933 | pubmed:issn | 0014-2999 | lld:pubmed |
| pubmed-article:1425933 | pubmed:author | pubmed-author:BoydJ FJF | lld:pubmed |
| pubmed-article:1425933 | pubmed:author | pubmed-author:HeitkemperM... | lld:pubmed |
| pubmed-article:1425933 | pubmed:author | pubmed-author:GruverM KMK | lld:pubmed |
| pubmed-article:1425933 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1425933 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:1425933 | pubmed:volume | 217 | lld:pubmed |
| pubmed-article:1425933 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1425933 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1425933 | pubmed:pagination | 127-35 | lld:pubmed |
| pubmed-article:1425933 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:meshHeading | pubmed-meshheading:1425933-... | lld:pubmed |
| pubmed-article:1425933 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1425933 | pubmed:articleTitle | Mediation of thyrotropin-releasing hormone induced gastric motility increases in developing rats. | lld:pubmed |
| pubmed-article:1425933 | pubmed:affiliation | Department of Physiological Nursing, University of Washington, Seattle 98195. | lld:pubmed |
| pubmed-article:1425933 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1425933 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
