Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
46
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pubmed:dateCreated |
1992-12-18
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pubmed:abstractText |
Six weeks after a holiday trip to Yugoslavia, a previously well 48-year-old man developed a reddish-livid, firm nodule, 0.5 cm in diameter, on the proximal joint of the right thumb. A similar nodule appeared nearby, as well as over the left patella. Eleven additional nodules occurred over the next 4 months. His general health remained good and physical examination merely noted the liver edge palpable 3 cm below the costal margin. The histology of one of the nodules showed a tuberculoid, plasma-rich inflammatory reaction reminiscent of leishmaniasis or brucellosis. No organisms were seen. Immunohistochemistry of a frozen section demonstrated Leishmania-associated antigens, and the Western-blot test was characteristic for leishmaniasis. No systemic treatment was undertaken because of likely alcoholic toxic liver damage. On local treatment with paromomycin-containing ointment the cutaneous nodules healed without scar within 3 months.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0012-0472
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
13
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1752-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1425295-Animals,
pubmed-meshheading:1425295-Antigens, Protozoan,
pubmed-meshheading:1425295-Blotting, Western,
pubmed-meshheading:1425295-Diagnosis, Differential,
pubmed-meshheading:1425295-Humans,
pubmed-meshheading:1425295-Immunohistochemistry,
pubmed-meshheading:1425295-Leishmania,
pubmed-meshheading:1425295-Leishmaniasis, Cutaneous,
pubmed-meshheading:1425295-Male,
pubmed-meshheading:1425295-Middle Aged,
pubmed-meshheading:1425295-Ointments,
pubmed-meshheading:1425295-Paromomycin
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pubmed:year |
1992
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pubmed:articleTitle |
[Leishmaniasis with multiple cutaneous nodules].
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pubmed:affiliation |
Dermatologische Universitätsklinik, Universität Erlangen.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|