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pubmed-article:1424890pubmed:abstractTextIncidence and potential risk factors for pneumonia due to Haemophilus influenzae in adults treated with mechanical ventilation in a medical-surgical ICU were investigated. Diagnosis was established in 91 episodes and H influenzae was isolated in 20 of them. Mean onset of ventilator-associated pneumonia (VAP) due to H influenzae was 10.8 days after intubation. Six patients with H influenzae VAP died in the ICU. Of 13 risk factors for developing VAP due to H influenzae, an absence of prior antibiotic treatment was the only variable which had statistical significance (p < 0.001). In these mechanically ventilated patients, Haemophilus influenzae was a common causative agent for VAP, frequently associated with Gram-positive cocci. Episodes of H influenzae VAP were associated with a lower mortality compared with other etiologies. The epidemiologic and clinical findings indicate that patients without a prior antimicrobial treatment have increased susceptibility to infections of the airway by H influenzae.lld:pubmed
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pubmed-article:1424890pubmed:articleTitlePneumonia due to Haemophilus influenzae among mechanically ventilated patients. Incidence, outcome, and risk factors.lld:pubmed
pubmed-article:1424890pubmed:affiliationIntensive Care Department, Hospital de la S. Creu i S. Pau., Universitat Autonoma de Barcelona, Spain.lld:pubmed
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