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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1992-12-14
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pubmed:abstractText |
Although hyperbaric oxygen therapy is clinically used for the treatment of several types of ischemic brain injury, few basic animal studies are available that provide a rationale for this therapy for complete global brain ischemia. Therefore, we investigated the effect of hyperbaric oxygen therapy on neurologic recovery after 15-min complete global cerebral ischemia in a canine model. Complete global ischemia was induced in 19 dogs by occlusion of the ascending aorta and the caval veins. Nine dogs were randomized to treatment with hyperbaric oxygenation (3 atmospheres absolute, 100% oxygen for 1 hr) at 3, 24, and 29 hrs after ischemia under spontaneous respiration, while the other ten dogs served as the control group without hyperbaric oxygen therapy (group C). Neurologic recovery was evaluated based on the electroencephalogram (EEG) activity score (1 = normal; 5 = isoelectric) and the neurologic recovery score (100 = normal; 0 = brain death) over a 14-day postischemic period.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0090-3493
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1588-94
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1424704-Animals,
pubmed-meshheading:1424704-Blood Gas Analysis,
pubmed-meshheading:1424704-Blood Glucose,
pubmed-meshheading:1424704-Body Temperature,
pubmed-meshheading:1424704-Brain Ischemia,
pubmed-meshheading:1424704-Disease Models, Animal,
pubmed-meshheading:1424704-Dogs,
pubmed-meshheading:1424704-Electroencephalography,
pubmed-meshheading:1424704-Evaluation Studies as Topic,
pubmed-meshheading:1424704-Hematocrit,
pubmed-meshheading:1424704-Hemodynamics,
pubmed-meshheading:1424704-Hyperbaric Oxygenation,
pubmed-meshheading:1424704-Neurologic Examination,
pubmed-meshheading:1424704-Severity of Illness Index,
pubmed-meshheading:1424704-Survival Rate,
pubmed-meshheading:1424704-Time Factors,
pubmed-meshheading:1424704-Treatment Outcome
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pubmed:year |
1992
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pubmed:articleTitle |
Hyperbaric oxygen therapy accelerates neurologic recovery after 15-minute complete global cerebral ischemia in dogs.
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pubmed:affiliation |
Department of Anesthesiology, Tohoku University School of Medicine, Sendai, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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