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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1992-12-23
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pubmed:abstractText |
Two enzyme immunoassays (EIAs) detecting Chlamydia trachomatis from endocervical swabs, Syva MicroTrak (MT) and Abbott Chlamydiazyme (CZ), were compared with a tissue culture (TC) standard. Initially, 8% (100 of 1250) of specimens were TC positive, yielding sensitivities of 94% (94 of 100) for MT and 79% (79 of 100) for CZ with identical 98% specificities (1129 of 1150 for MT and 1130 of 1150 for CZ). Discrepant specimens were retested by both EIAs and assayed for elementary bodies (EBs) by a fluorescent antibody test. After discrepancy analysis, 9.5% (118) of 1240 patients were either TC or EB positive, yielding sensitivities of 94.1% for MT (111 of 118) and 79.7% for CZ (94 of 118) with identical specificities of 100% (1122 of 1122). These results indicate that the MT is significantly more sensitive (p less than 0.05, McNemar test) than CZ in detecting C. trachomatis from endocervical swabs.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0732-8893
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
579-86
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1424514-Adolescent,
pubmed-meshheading:1424514-Adult,
pubmed-meshheading:1424514-Child,
pubmed-meshheading:1424514-Chlamydia Infections,
pubmed-meshheading:1424514-Chlamydia trachomatis,
pubmed-meshheading:1424514-Culture Techniques,
pubmed-meshheading:1424514-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1424514-Evaluation Studies as Topic,
pubmed-meshheading:1424514-False Negative Reactions,
pubmed-meshheading:1424514-False Positive Reactions,
pubmed-meshheading:1424514-Female,
pubmed-meshheading:1424514-Fluorescent Antibody Technique,
pubmed-meshheading:1424514-Humans,
pubmed-meshheading:1424514-Sensitivity and Specificity,
pubmed-meshheading:1424514-Vaginal Smears
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pubmed:articleTitle |
Evaluation of two ELISA's for detecting Chlamydia trachomatis from endocervical swabs.
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pubmed:affiliation |
Department of Pediatrics, State University of New York, Buffalo School of Medicine and Biological Sciences.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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