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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1992-12-9
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pubmed:abstractText |
The effects of two polysaccharides, AT-HW and AT-AL obtained from the fruiting bodies of Armillariella tabescens on murine sarcoma 180 tumor and peritoneal macrophages were examined at intraperitoneal administration. AT-HW from the hot-water extract and AT-AL from the alkaline extract significantly inhibited the tumor, and the results of different administration schedule and phagocytic system blockade suggested that the mechanism of AT-AL differed from that of AT-HW and branched (1----3)-beta-D-glucans. AT-HW and AT-AL showed reticuloendothelial system-potentiating activity, increased the number of peritoneal exudate cells, activated on macrophages (acid phosphatase activity, glucose consumption, superoxide anion production), and enhanced mitogenic reaction, although AT-HW did not produce superoxide anion in vitro.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0009-2363
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2110-4
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1423764-Adjuvants, Immunologic,
pubmed-meshheading:1423764-Animals,
pubmed-meshheading:1423764-Antineoplastic Agents,
pubmed-meshheading:1423764-Basidiomycota,
pubmed-meshheading:1423764-Macrophages,
pubmed-meshheading:1423764-Male,
pubmed-meshheading:1423764-Mice,
pubmed-meshheading:1423764-Mice, Inbred Strains,
pubmed-meshheading:1423764-Polysaccharides,
pubmed-meshheading:1423764-Tumor Cells, Cultured
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pubmed:year |
1992
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pubmed:articleTitle |
Polysaccharides in fungi. XXX. Antitumor and immunomodulating activities of two polysaccharides from the fruiting bodies of Armillariella tabescens.
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pubmed:affiliation |
Gifu Pharmaceutical University, Japan.
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pubmed:publicationType |
Journal Article
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