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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1992-12-9
|
| pubmed:abstractText |
A 3D optimized, refocused HNCA experiment is described. It is demonstrated to yield a dramatic increase in sensitivity when applied to [13C, 15N]-labeled human carbonic anhydrase II, a 29-kDa protein. The reasons for the gain in sensitivity are discussed, and 3 distinct areas for further development are indicated.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0925-2738
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
195-202
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:1422152-Carbon Isotopes,
pubmed-meshheading:1422152-Carbonic Anhydrases,
pubmed-meshheading:1422152-Humans,
pubmed-meshheading:1422152-Isoenzymes,
pubmed-meshheading:1422152-Magnetic Resonance Spectroscopy,
pubmed-meshheading:1422152-Mathematics,
pubmed-meshheading:1422152-Nitrogen Isotopes,
pubmed-meshheading:1422152-Protein Conformation
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
A refocused and optimized HNCA: increased sensitivity and resolution in large macromolecules.
|
| pubmed:affiliation |
Department of Research and Development, Varian Associates, Palo Alto, CA 94304.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|