|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
1992-12-23
|
|
pubmed:abstractText |
Velnacrine testing for tolerance and safety in both normal elderly subjects and patients with Alzheimer's disease (AD) is reviewed to illustrate the importance of Phase I trials in the target group as more predictive of safety and tolerance for subsequent multicenter trials than those conducted in healthy elderly subjects.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
1060-0280
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
26
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1118-22
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:1421679-Aged,
pubmed-meshheading:1421679-Aged, 80 and over,
pubmed-meshheading:1421679-Alzheimer Disease,
pubmed-meshheading:1421679-Cholinesterase Inhibitors,
pubmed-meshheading:1421679-Double-Blind Method,
pubmed-meshheading:1421679-Drug Administration Schedule,
pubmed-meshheading:1421679-Humans,
pubmed-meshheading:1421679-Male,
pubmed-meshheading:1421679-Middle Aged,
pubmed-meshheading:1421679-Tacrine
|
|
pubmed:year |
1992
|
|
pubmed:articleTitle |
Implications of the study population in the early evaluation of anticholinesterase inhibitors for Alzheimer's disease.
|
|
pubmed:affiliation |
California Clinical Trials, Beverly Hills 90211.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|
