Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1992-12-1
|
pubmed:abstractText |
In staphylococcal infection the changes in functional ability of macrophages occur: their oxygen-depending bactericidity and adenosine-desaminase activity are depressed 5-nucleotidase ability increases. Introduction of homologous alpha-IFN in the dose of 1 x 10(3) u/mouse leads to enhancing macrophage bactericidity of the animals infected, inhibits their 5-nucleotidase activity and enhances adenosine desaminase one. Influence of alpha-IFN on the activity of adenosine metabolism enzymes in macrophages can be considered one of the most important mechanisms of its modulating effect in bacterial infections.
|
pubmed:language |
rus
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0365-9615
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
114
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
63-6
|
pubmed:dateRevised |
2008-10-8
|
pubmed:meshHeading |
pubmed-meshheading:1421314-5'-Nucleotidase,
pubmed-meshheading:1421314-Adenosine Deaminase,
pubmed-meshheading:1421314-Animals,
pubmed-meshheading:1421314-Blood Bactericidal Activity,
pubmed-meshheading:1421314-Cells, Cultured,
pubmed-meshheading:1421314-Interferon-alpha,
pubmed-meshheading:1421314-Macrophages,
pubmed-meshheading:1421314-Mice,
pubmed-meshheading:1421314-Mice, Inbred CBA,
pubmed-meshheading:1421314-Staphylococcal Infections,
pubmed-meshheading:1421314-Time Factors
|
pubmed:year |
1992
|
pubmed:articleTitle |
[Effects of alpha-interferon on the level of adenosine metabolism enzymes and bactericidal activity of macrophages in staphylococcal infection].
|
pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|