Linked Life Data

1418392

Source:http://linkedlifedata.com/resource/pubmed/id/1418392

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1992-12-11
pubmed:abstractText
Thirty patient with allergic rhinitis sensitized to Parietaria pollen were enrolled in a double-blind clinical trial in order to evaluate whether the addition of nimesulide, a non-steroidal antiinflammatory drug, to standard antihistamine therapy may improve symptom relief. Patients were randomly divided in two groups: one was given terfenadine (120 mg/day) and nimesulide (200 mg/day), the other was given terfenadine (120 mg/day) and placebo. Both treatments lasted 30 days. Clinical efficacy was assessed by physical examination on 1st, 15th, 30th day of treatment, daily self-evaluation of symptom score, and patient's overall judgement at the end of the trial. The group receiving terfenadine + nimesulide reported a significant lower symptom score and gave a better overall evaluation than the group receiving terfenadine + placebo. These results suggest that the addition of nimesulide to antihistamine treatment may be useful to achieve a better relief of symptoms in allergic rhinitis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0397-9148
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
313-4, 317-9
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Combined treatment of allergic rhinitis with terfenadine and nimesulide, a non-steroidal antiinflammatory drug.
pubmed:affiliation
Servizio Autonomo di Allergologia, Istituti Ospitalieri di Verona, Italy.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial