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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
5
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|
pubmed:dateCreated |
1992-12-23
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|
pubmed:abstractText |
The effects of vigabatrin were studied over a 6-month period in 43 patients with intractable epilepsy. Children with complex partial seizures, with or without secondary generalization, responded best with more than one-half achieving a greater than 50% reduction; generalized tonic-clonic seizures also improved but there was no significant change in absence or myoclonic seizures. Four patients are seizure-free on monotherapy with vigabatrin. The drug was well tolerated with few side effects.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:issn |
0887-8994
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
338-40
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pubmed:dateRevised |
2006-5-23
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pubmed:meshHeading |
pubmed-meshheading:1418176-Adolescent,
pubmed-meshheading:1418176-Aminocaproic Acids,
pubmed-meshheading:1418176-Anticonvulsants,
pubmed-meshheading:1418176-Child,
pubmed-meshheading:1418176-Child, Preschool,
pubmed-meshheading:1418176-Electroencephalography,
pubmed-meshheading:1418176-Epilepsies, Myoclonic,
pubmed-meshheading:1418176-Epilepsies, Partial,
pubmed-meshheading:1418176-Epilepsy,
pubmed-meshheading:1418176-Epilepsy, Absence,
pubmed-meshheading:1418176-Epilepsy, Complex Partial,
pubmed-meshheading:1418176-Epilepsy, Tonic-Clonic,
pubmed-meshheading:1418176-Evoked Potentials,
pubmed-meshheading:1418176-Female,
pubmed-meshheading:1418176-Humans,
pubmed-meshheading:1418176-Infant,
pubmed-meshheading:1418176-Male,
pubmed-meshheading:1418176-Retrospective Studies,
pubmed-meshheading:1418176-Spasms, Infantile,
pubmed-meshheading:1418176-Vigabatrin
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pubmed:articleTitle |
Vigabatrin in intractable childhood epilepsy: a retrospective study.
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pubmed:affiliation |
Department of Neurology, Royal Liverpool Children's Hospital, Alder Hey, England.
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pubmed:publicationType |
Journal Article
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