rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
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pubmed:dateCreated |
1992-11-6
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pubmed:abstractText |
The synthesis of various pyrrylphenylethanones resembling cathinone and lefetamine is described starting from 2-chloro-1-(1-methyl-1H-pyrrol-2-yl)-2-phenylethan-1-one. Some derivatives showed good antinociceptic activity, comparable to that of morphine. The neuropsychopharmacological profile of title compounds has been also studied to explore their action on C.N.S.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alkaloids,
http://linkedlifedata.com/resource/pubmed/chemical/Analgesics,
http://linkedlifedata.com/resource/pubmed/chemical/Anticonvulsants,
http://linkedlifedata.com/resource/pubmed/chemical/Ketones,
http://linkedlifedata.com/resource/pubmed/chemical/Muscle Relaxants, Central,
http://linkedlifedata.com/resource/pubmed/chemical/Phenethylamines,
http://linkedlifedata.com/resource/pubmed/chemical/Psychotropic Drugs,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles,
http://linkedlifedata.com/resource/pubmed/chemical/cathinone,
http://linkedlifedata.com/resource/pubmed/chemical/lephetamine
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0365-6233
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
325
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
403-9
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1417455-Alkaloids,
pubmed-meshheading:1417455-Analgesics,
pubmed-meshheading:1417455-Animals,
pubmed-meshheading:1417455-Anticonvulsants,
pubmed-meshheading:1417455-Behavior, Animal,
pubmed-meshheading:1417455-Female,
pubmed-meshheading:1417455-Ketones,
pubmed-meshheading:1417455-Male,
pubmed-meshheading:1417455-Mice,
pubmed-meshheading:1417455-Muscle Relaxants, Central,
pubmed-meshheading:1417455-Phenethylamines,
pubmed-meshheading:1417455-Psychotropic Drugs,
pubmed-meshheading:1417455-Pyrroles
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pubmed:year |
1992
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pubmed:articleTitle |
Pyrrylphenylethanones related to cathinone and lefetamine: synthesis and pharmacological activities.
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pubmed:affiliation |
Dipartimento di Studi farmaceutici, Università di Roma, La Sapienza, Italy.
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pubmed:publicationType |
Journal Article
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