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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1992-11-18
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pubmed:abstractText |
Between June 1968 and April 1991, 75 patients who had undergone coronary angiography underwent repair of a postinfarction ventricular septal defect. Group 1 (n = 33) includes patients who had two- or three-vessel serious (> 75% narrowing) proximal coronary artery disease and underwent complete revascularization in addition to repair of the ventricular septal defect. Group 2 (n = 19) patients also had two- or three-vessel coronary artery disease but bypass grafting was not performed; only the ventricular defect was repaired. Group 3 (n = 23) patients had only single-vessel coronary artery disease that corresponded to the region of the infarct; they underwent ventricular septal defect repair only. Follow-up of hospital survivors was 96% complete at a mean of 86.2 months (range, 1 to 288 months). Hospital mortality after ventricular septal defect repair was 21.2% in the cohort with bypassed coronary artery disease (group 1), 26.3% in those with unbypassed disease (group 2), and 26.1% in those with only single-vessel coronary artery disease (group 3) (p = 0.88). With follow-up after 5 and 10 years, the actuarial survival was 72.2% +/- 8% and 47.8% +/- 10%, respectively, in the bypassed group, 29.2% +/- 11% and 0%, respectively, in the unbypassed group, and 52.2% +/- 10% and 36.5% +/- 11%, respectively, in the cohort with single-vessel disease. Bypassing associated coronary artery disease significantly increased long-term survival when compared with patients with unbypassed coronary artery disease (p = 0.0015).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0003-4975
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
876-82; discussion 882-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1417278-Aged,
pubmed-meshheading:1417278-Coronary Artery Bypass,
pubmed-meshheading:1417278-Coronary Disease,
pubmed-meshheading:1417278-Female,
pubmed-meshheading:1417278-Heart Rupture, Post-Infarction,
pubmed-meshheading:1417278-Heart Septum,
pubmed-meshheading:1417278-Heart Ventricles,
pubmed-meshheading:1417278-Humans,
pubmed-meshheading:1417278-Male,
pubmed-meshheading:1417278-Middle Aged,
pubmed-meshheading:1417278-Survival Rate
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pubmed:year |
1992
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pubmed:articleTitle |
Postinfarct ventricular septal defect repair: effect of coronary artery bypass grafting.
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pubmed:affiliation |
Surgical Cardiovascular Unit, Massachusetts General Hospital, Harvard Medical School, Boston 02114.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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