Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1992-11-10
pubmed:abstractText
Fungal infections and antifungal resistance are increasingly recognized. Antifungal susceptibility testing remains unstandardized, and a particularly important problem is endpoint determination. In this paper we propose the yeast metabolic reduction of the tetrazolium salt 2,3-bis(2- methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetraz olium hydroxide (XTT) as a colorimetric endpoint which is quantitative and objective. Amphotericin B, fluorocytosine, and fluconazole dose-response curves were obtained, and a metabolic MIC could be determined by using precise criteria.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-1864923, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-2285276, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-2332282, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-2495366, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-2788039, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-2846651, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-2917126, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-3049651, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-3300534, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-3317728, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-3326524, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-3335022, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-3409223, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-3904613, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-6606682, http://linkedlifedata.com/resource/pubmed/commentcorrection/1416843-792958
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0066-4804
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1619-25
pubmed:dateRevised
2010-9-7
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Innovative endpoint determination system for antifungal susceptibility testing of yeasts.
pubmed:affiliation
Department of Microbiology, Toronto Hospital, Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't