| pubmed-article:1416076 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1416076 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:1416076 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:1416076 | lifeskim:mentions | umls-concept:C0010453 | lld:lifeskim |
| pubmed-article:1416076 | lifeskim:mentions | umls-concept:C0029418 | lld:lifeskim |
| pubmed-article:1416076 | lifeskim:mentions | umls-concept:C0029463 | lld:lifeskim |
| pubmed-article:1416076 | lifeskim:mentions | umls-concept:C0521457 | lld:lifeskim |
| pubmed-article:1416076 | lifeskim:mentions | umls-concept:C2828027 | lld:lifeskim |
| pubmed-article:1416076 | lifeskim:mentions | umls-concept:C1845292 | lld:lifeskim |
| pubmed-article:1416076 | lifeskim:mentions | umls-concept:C0312558 | lld:lifeskim |
| pubmed-article:1416076 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:1416076 | pubmed:dateCreated | 1992-11-10 | lld:pubmed |
| pubmed-article:1416076 | pubmed:abstractText | Immunohistochemical staining techniques used on an 11-week-old fetus showed that fetal antigen 2 (FA2) was present intracellularly in endochondral and perichondral osteoblasts, and the immunoreaction was extended into the adjacent bone matrix. Osteoclasts and chondroblasts were found to be FA2 negative. A granular perinuclear intracytoplasmic FA2 immunoreaction was found in cultured osteoblasts and osteogenic osteosarcoma cells, and immunoelectron-microscopical examination revealed a granular immunoreaction product in the rough endoplasmic reticulum. These findings indicate that FA2 is synthesized by osteoblasts and osteogenic osteosarcoma cells. A reaction of immunological identity was found between FA2 purified from second trimester amniotic fluid and serum-free supernatants of cultured osteogenic osteosarcoma cells. This shows that an antigen recognized by the anti FA2 antibody is secreted by these malignant cells. Thus, FA2 may represent a marker for altered bone metabolism, and have a potential in the classification of osteogenic osteosarcoma/chondrosarcoma. | lld:pubmed |
| pubmed-article:1416076 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1416076 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1416076 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1416076 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1416076 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1416076 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1416076 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1416076 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1416076 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:1416076 | pubmed:issn | 0340-2061 | lld:pubmed |
| pubmed-article:1416076 | pubmed:author | pubmed-author:TeisnerBB | lld:pubmed |
| pubmed-article:1416076 | pubmed:author | pubmed-author:ChemnitzJJ | lld:pubmed |
| pubmed-article:1416076 | pubmed:author | pubmed-author:RasmussenH... | lld:pubmed |
| pubmed-article:1416076 | pubmed:author | pubmed-author:KasselNN | lld:pubmed |
| pubmed-article:1416076 | pubmed:author | pubmed-author:TornehaveDD | lld:pubmed |
| pubmed-article:1416076 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1416076 | pubmed:volume | 186 | lld:pubmed |
| pubmed-article:1416076 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1416076 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1416076 | pubmed:pagination | 271-4 | lld:pubmed |
| pubmed-article:1416076 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:meshHeading | pubmed-meshheading:1416076-... | lld:pubmed |
| pubmed-article:1416076 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1416076 | pubmed:articleTitle | Fetal antigen 2 (FA2) in human fetal osteoblasts, cultured osteoblasts and osteogenic osteosarcoma cells. | lld:pubmed |
| pubmed-article:1416076 | pubmed:affiliation | Department of Human Anatomy, Odense University, Denmark. | lld:pubmed |
| pubmed-article:1416076 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1416076 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
