Linked Life Data

1414589

Source:http://linkedlifedata.com/resource/pubmed/id/1414589

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1992-11-25
pubmed:abstractText
Hydrocortisone (HC) ameliorated the course of experimental infection with E. coli given intraperitoneally. In experiments with Staphylococcus aureus and treatment with endotoxin on the day of infection, HC had also a beneficial effect, however only when LPS was injected intraperitoneally and bacteria intravenously. With the footpad swelling reaction as a model for cellular immunity it could be shown that HC alone reduced the reactivity by 75 per cent. Under endotoxin treatment, however, HC induced further inhibition when LPS was given intraperitoneally the day of sensitization but changing to a stimulatory effect when LPS was given two days later. In case of intravenous application of LPS, HC had no effect.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-2598
pubmed:author
pubmed:issnType
Print
pubmed:volume
319
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
137-43
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
"Inverse" effects of cortisone in experimental infection of mice.
pubmed:affiliation
Department of medical Microbiology, Faculty of Medicine, University of Aachen, Federal Republic of Germany.
pubmed:publicationType
Journal Article