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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1977-8-25
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pubmed:abstractText |
A significant increase in the NaBH4 reducible intermolecular cross-links in the 9 week immobilized rabbit periarticular connective tissue was found. Dihydroxylysinonorleucine, hydroxylysinonorleucine, and histidinohydroxymerodesmosine were the major cross-links which increased during the period of immobilization. No change in the hydroxlysine/lysine ratio between the immobilized and control periarticular connective tissue collagen was detected during the 9 weeks of enforced immobilization of the rabbit knee. Since the collagen mass in the immobilized periarticular connective tissue does not change, or at most is reduced 10%, we suggest that there is an increase in collagen cross-links expressed both in per unit weight of collagen and on the basis of collagen mass per knee due to the lack of physical stress and motion.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-8207
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:141358-Amino Acids,
pubmed-meshheading:141358-Animals,
pubmed-meshheading:141358-Collagen,
pubmed-meshheading:141358-Connective Tissue,
pubmed-meshheading:141358-Hindlimb,
pubmed-meshheading:141358-Immobilization,
pubmed-meshheading:141358-Joints,
pubmed-meshheading:141358-Male,
pubmed-meshheading:141358-Protein Conformation,
pubmed-meshheading:141358-Rabbits
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pubmed:year |
1977
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pubmed:articleTitle |
Collagen cross-linking alterations in joint contractures: changes in the reducible cross-links in periarticular connective tissue collagen after nine weeks of immobilization.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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