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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1964-6-1
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pubmed:abstractText |
Guinea pigs fed picryl chloride to induce specific immunologic unresponsiveness cleared small amounts of venously infused antipicryl antibody at a rate equal to that of normal guinea pigs. Catabolism of passively administered picryl-specific antibody did not alter the unresponsive state of picryl chloride-fed guinea pigs or the responsive state of normal guinea pigs. Lymphoid cells of picryl chloride immunized guinea pigs produced equal amounts of picryl-specific antibody in picryl chloride-fed and normal animals. Allergen-fed guinea pigs remained unresponsive to attempted sensitization with the allergen in excess of 10 months after the final feeding, though some became feebly sensitive between 9 and 11 months. Second attempts to make unresponsive animals hypersensitive were unsuccessful. White blood cells of guinea pigs unresponsive to picryl chloride were unable to transfer delayed-type hypersensitivity for picryl chloride to normal recipients yet readily transferred tuberculin hypersensitivity.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13099277,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13124925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13163409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13183684,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13405691,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13631253,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13641356,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13767458,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13812629,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13815912,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13887798,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13935538,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-13966867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-14013739,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-14021926,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-14050203,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-14354192,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-14354199,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-14401944,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-14803635,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-15395570,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14112263-19871087
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pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/ANAPHYLAXIS,
http://linkedlifedata.com/resource/pubmed/keyword/ANTIBODY FORMATION,
http://linkedlifedata.com/resource/pubmed/keyword/ANTIGEN-ANTIBODY REACTIONS,
http://linkedlifedata.com/resource/pubmed/keyword/ANTIGENS,
http://linkedlifedata.com/resource/pubmed/keyword/CHLORIDES,
http://linkedlifedata.com/resource/pubmed/keyword/EXPERIMENTAL LAB STUDY,
http://linkedlifedata.com/resource/pubmed/keyword/GUINEA PIGS,
http://linkedlifedata.com/resource/pubmed/keyword/HEMAGGLUTINATION,
http://linkedlifedata.com/resource/pubmed/keyword/HYPERSENSITIVITY,
http://linkedlifedata.com/resource/pubmed/keyword/LEUKOCYTES,
http://linkedlifedata.com/resource/pubmed/keyword/LYMPH NODES,
http://linkedlifedata.com/resource/pubmed/keyword/PICRATES,
http://linkedlifedata.com/resource/pubmed/keyword/SKIN TESTS,
http://linkedlifedata.com/resource/pubmed/keyword/SPLEEN,
http://linkedlifedata.com/resource/pubmed/keyword/TUBERCULIN
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
OM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-1007
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1021-35
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pubmed:dateRevised |
2010-9-20
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pubmed:meshHeading |
pubmed-meshheading:14112263-Anaphylaxis,
pubmed-meshheading:14112263-Antibody Formation,
pubmed-meshheading:14112263-Antigen-Antibody Reactions,
pubmed-meshheading:14112263-Antigens,
pubmed-meshheading:14112263-Chlorides,
pubmed-meshheading:14112263-Guinea Pigs,
pubmed-meshheading:14112263-Hemagglutination,
pubmed-meshheading:14112263-Hypersensitivity,
pubmed-meshheading:14112263-Leukocytes,
pubmed-meshheading:14112263-Lymph Nodes,
pubmed-meshheading:14112263-Picrates,
pubmed-meshheading:14112263-Research,
pubmed-meshheading:14112263-Skin Tests,
pubmed-meshheading:14112263-Spleen,
pubmed-meshheading:14112263-Tuberculin
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pubmed:year |
1963
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pubmed:articleTitle |
IMMUNOLOGICAL UNRESPONSIVENESS TO SENSITIZATION WITH SIMPLE CHEMICAL COMPOUNDS; A SEARCH FOR ANTIBODY-ABSORBING DEPOTS OF ALLERGEN.
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pubmed:publicationType |
Journal Article
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