Linked Life Data

1409922

Source:http://linkedlifedata.com/resource/pubmed/id/1409922

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1992-11-10
pubmed:abstractText
The role of gastric secretion in drinking was investigated. Treatment of pigs with cimetidine (300 mg IV), which inhibits gastric secretion, did not change the level of feed or water intake, or alter the temporal relationship between eating and drinking. Gastric infusions of 0.15 M HCl (5 ml.kg-1.h-1) did not increase drinking. Pentagastrin infusion (0.05 microgram.kg-1.min-1) increased water intake in some, but not all pigs during a 1-hour infusion. Plasma protein levels increased significantly during 1-hour pentagastrin infusions (0.05 microgram.kg-1.min-1), indicating an estimated fall in blood volume of 2.5%. Captopril (1.75 mg/kg IV), which blocks the renin-angiotensin system, abolished pentagastrin-stimulated drinking. It was concluded that gastric secretion does not play a direct role in normal, periprandial drinking but that in pigs the renin-angiotensin system is involved in pentagastrin-stimulated drinking.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
569-76
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
The mechanism and significance of pentagastrin-stimulated water intake in the pig.
pubmed:affiliation
Department of Physiology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.