Linked Life Data

1409787

Source:http://linkedlifedata.com/resource/pubmed/id/1409787

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1992-11-18
pubmed:abstractText
Domestic fowl tested at 3, 5, and 7 days posthatch jumped from a heated grid more rapidly than animals tested at 14 days posthatch. Morphine (2.5 mg/kg) decreased jump latency in 14-day-old chicks but did not significantly affect jump latency in younger chicks. Respiration was lower in 3-day-old chicks than in the older groups but morphine depressed respiration at each age. In a second experiment morphine significantly decreased jump response latency in 5-day-old chicks when thermal stimulus intensity was lowered and morphine dose increased (5 mg/kg). Posttest respiration rate was depressed by morphine. Morphine hyperalgesia and respiratory depression were reversed by naloxone (5 mg/kg). However, naloxone alone increased jump response latency. Young domestic fowl are more sensitive and/or reactive to a noxious thermal stimulus and are less sensitive to morphine than 14-day-old chicks but morphine hyperalgesia was evident in both 5- and 14-day-old chicks. These hyperalgesic chicks may be tolerant at birth to morphine hypoalgesic effects on nociception.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
535-9
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Morphine hyperalgesic effects on developmental changes in thermal nociception and respiration in domestic fowl (Gallus gallus).
pubmed:affiliation
Department of Psychology, Iowa State University, Ames 50011-3180.
pubmed:publicationType
Journal Article