|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1992-10-26
|
|
pubmed:abstractText |
A receptor for neurite outgrowth factor (82 kDa membrane protein, NOFR) was detected in the developing chick cerebellum by immuno- and ligand blots. In immunohistochemical study, NOFR was maximally expressed in the external granular layer of cerebellum at embryonic day 10-12 and gradually decreased until embryonic day 18. Neurite outgrowth and cell migration induced by NOF from cerebellar explants were completely suppressed by the addition of anti-NOFR IgG. These results suggest that NOFR plays an important role in the cerebellar neurogenesis.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0304-3940
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
8
|
|
pubmed:volume |
140
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
78-80
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:1407705-Animals,
pubmed-meshheading:1407705-Cerebellum,
pubmed-meshheading:1407705-Chick Embryo,
pubmed-meshheading:1407705-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:1407705-Embryonic and Fetal Development,
pubmed-meshheading:1407705-Immunoglobulin G,
pubmed-meshheading:1407705-Immunohistochemistry,
pubmed-meshheading:1407705-Molecular Weight,
pubmed-meshheading:1407705-Nerve Growth Factors,
pubmed-meshheading:1407705-Neurites,
pubmed-meshheading:1407705-Organ Culture Techniques,
pubmed-meshheading:1407705-Receptors, Growth Factor,
pubmed-meshheading:1407705-Receptors, Immunologic
|
|
pubmed:year |
1992
|
|
pubmed:articleTitle |
Involvement of a receptor for neurite outgrowth factor (NOFR) in cerebellar neurogenesis.
|
|
pubmed:affiliation |
Department of Pharmacology, Osaka University School of Medicine, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
