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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
1992-11-23
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pubmed:abstractText |
Recent reports of the dramatic antitumor effect of all-trans-retinoic acid (RA) in patients with acute promyelocytic leukemia (APL) have renewed interest in the oncologic indications for retinoids. Furthermore, a variety of pediatric tumors are responsive to RA in vitro, which provides additional rationale for a phase I evaluation of RA in children with cancer that is refractory to standard therapy.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0732-183X
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
1666-73
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1403049-Administration, Oral,
pubmed-meshheading:1403049-Adolescent,
pubmed-meshheading:1403049-Adult,
pubmed-meshheading:1403049-Capsules,
pubmed-meshheading:1403049-Child,
pubmed-meshheading:1403049-Child, Preschool,
pubmed-meshheading:1403049-Cohort Studies,
pubmed-meshheading:1403049-Drug Administration Schedule,
pubmed-meshheading:1403049-Half-Life,
pubmed-meshheading:1403049-Humans,
pubmed-meshheading:1403049-Neoplasms,
pubmed-meshheading:1403049-Pseudotumor Cerebri,
pubmed-meshheading:1403049-Tretinoin
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pubmed:year |
1992
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pubmed:articleTitle |
Phase I and pharmacokinetic evaluation of all-trans-retinoic acid in pediatric patients with cancer.
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pubmed:affiliation |
Pediatric Branch, National Cancer Institute, Bethesda, MD 20892.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Clinical Trial, Phase I
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