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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
|
pubmed:dateCreated |
1992-11-6
|
pubmed:abstractText |
The case of a patient with progressive systemic sclerosis, who developed hypoglycaemia and insulin autoantibodies, is described. Repeated blood glucose measurements showed levels less than 2.8 mmol/l. High immunoreactive insulin levels, with undetectable free insulin, led to the discovery of anti-insulin antibodies in the patient's serum. He had no history of exogenous insulin use and was receiving penicillamine treatment. A double mechanism for the autoimmune insulin syndrome in this case is proposed: acting in a patient with increased humoral immunoresponsiveness, penicillamine might have induced the development of insulin autoantibodies.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0301-0163
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
37
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
78-80
|
pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:1398479-Adult,
pubmed-meshheading:1398479-Autoantibodies,
pubmed-meshheading:1398479-Autoimmune Diseases,
pubmed-meshheading:1398479-Blood Glucose,
pubmed-meshheading:1398479-Humans,
pubmed-meshheading:1398479-Insulin,
pubmed-meshheading:1398479-Male,
pubmed-meshheading:1398479-Penicillamine
|
pubmed:year |
1992
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pubmed:articleTitle |
Autoimmune insulin syndrome in a patient with progressive systemic sclerosis receiving penicillamine.
|
pubmed:affiliation |
Division of Endocrinology, Fundación Jimenz Diaz, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Case Reports
|