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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-11-10
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pubmed:abstractText |
Primary cultures of rat dorsal root ganglionic (DRG) cells were stained with isoform-specific antibodies against non-muscle myosin II. Antibodies against the brain type myosin (MIIB) stained the peripheries of growth cones and non-neuronal cells. Double staining of the cells with the anti-myosin antibodies and rhodamine-phalloidin or anti-actin antibodies indicated that MIIB co-exists, with F-actin, at the leading edge. Antibodies against platelet myosin stained neither leading edges nor neurites, but stained the cell bodies of neurons and the stress fibers of non-neuronal cells. These results suggest that MIIB functions in the motility of the leading edge of DRG cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
311
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
91-4
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:1397310-Animals,
pubmed-meshheading:1397310-Cell Division,
pubmed-meshheading:1397310-Cells, Cultured,
pubmed-meshheading:1397310-Fluorescent Antibody Technique,
pubmed-meshheading:1397310-Ganglia, Spinal,
pubmed-meshheading:1397310-Myosins,
pubmed-meshheading:1397310-Neurites,
pubmed-meshheading:1397310-Neurons,
pubmed-meshheading:1397310-Rats
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pubmed:year |
1992
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pubmed:articleTitle |
Localization of myosin IIB at the leading edge of growth cones from rat dorsal root ganglionic cells.
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pubmed:affiliation |
Department of Anatomy and Cell Biology, SUNY, HSC, Brooklyn.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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