Linked Life Data

1396996

Source:http://linkedlifedata.com/resource/pubmed/id/1396996

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1992-11-13
pubmed:abstractText
Beta-endorphin (4 micrograms) injected i.v.t. induced the release of immunoreactive [Met5]enkephalin and sulfated cholecystokinin octapeptide (CCK-8s) from the spinal cord in the pentobarbital-anesthetized rat. The inhibition of the tail-flick response induced by beta-endorphin given i.v.t. was antagonized by i.t. injection of CCK-8s and potentiated by i.t. administration of the antibody to CCK-8s. The findings give support to the hypothesis that endogenous CCK-8s in the spinal cord may play a negative feedback role in modulating beta-endorphin-induced antinociception.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
215
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
309-12
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Release of immunoreactive [Met5]enkephalin and cholecystokinin from the spinal cord by beta-endorphin administered intraventricularly in the pentobarbital-anesthetized rat.
pubmed:affiliation
Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee 53226.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.