Linked Life Data

1394911

Source:http://linkedlifedata.com/resource/pubmed/id/1394911

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1992-10-26
pubmed:abstractText
Hybridomas producing monoclonal antibodies (McAb) directed against Trichomonas vaginalis have been produced by fusing NSI myeloma cells with spleen cells of BALB/c mice immunized with Trichomonas vaginalis. IFA technique was used to test the binding activity of four McAbs produced. The McAb belonged to the IgG subtypes IgG1 (2A2, 2A4 McAb), IgG3 (2H9 McAb) and IgG 2b (2A12 McAb). Three McAbs, designated 2A2, 2A4, 2A12, reacted with a surface membrane component of live Trichomonas vaginalis. One (2A12) of them produced complement-dependent cytolysis of the parasites. Others (2A2,2A4) produced complement-independent cytotoxicity of the parasites. 2H9 McAb which reacted with the nucleus of the organisms did not agglutinate the parasites. The four McAbs which did not have cross reaction with some protozoa of Zoomastigophorea species were specific antibodies against Trichomonas vaginalis. (Figs. 1-3).
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1000-7423
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
139-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
[Preparation and identification of anti-Trichomonas vaginalis monoclonal antibodies].
pubmed:affiliation
Department of Parasitology, Beijing Medical University.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't