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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1992-11-20
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pubmed:abstractText |
alpha- And beta-glucoside derivatives of validamine and valienamine were prepared by enzymatic transglucosidation using alpha- and beta-glucosidase of Rhodotorula lactosa. The structures of these derivatives have been elucidated by 13C- and 1H-nuclear magnetic resonance spectral analysis. Thus, 7-alpha-glucoside, 7-alpha-isomaltoside, and 4-alpha-glucoside of validamine and 7-alpha-glucoside, 7-alpha-isomaltoside, 4-alpha-glucoside, and 4-alpha-isomaltoside of valienamine were obtained from maltose and validamine or valienamine using alpha-glucosidase. 7-beta-glucoside, 2-beta-glucoside, and 4-beta-glucoside of validamine or valienamine were obtained from cellobiose and validamine or valienamine using beta-glucosidase. These derivatives were tested for alpha-glucosidase inhibitory activity on rat small intestinal glycosidases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cyclohexenes,
http://linkedlifedata.com/resource/pubmed/chemical/Glucosides,
http://linkedlifedata.com/resource/pubmed/chemical/Hexosamines,
http://linkedlifedata.com/resource/pubmed/chemical/Inositol,
http://linkedlifedata.com/resource/pubmed/chemical/alpha-Glucosidases,
http://linkedlifedata.com/resource/pubmed/chemical/validamine,
http://linkedlifedata.com/resource/pubmed/chemical/valienamine
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0009-2363
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1871-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1394706-Animals,
pubmed-meshheading:1394706-Cyclohexenes,
pubmed-meshheading:1394706-Glucosides,
pubmed-meshheading:1394706-Hexosamines,
pubmed-meshheading:1394706-Inositol,
pubmed-meshheading:1394706-Male,
pubmed-meshheading:1394706-Microvilli,
pubmed-meshheading:1394706-Rats,
pubmed-meshheading:1394706-Rats, Wistar,
pubmed-meshheading:1394706-alpha-Glucosidases
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pubmed:year |
1992
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pubmed:articleTitle |
Enzymatic synthesis of glucoside derivatives of validamine and valienamine.
|
pubmed:affiliation |
Faculty of Pharmacy, Hokuriku University, Ishikawa, Japan.
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pubmed:publicationType |
Journal Article,
In Vitro
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