Source:http://linkedlifedata.com/resource/pubmed/id/13944005
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1963-12-1
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pubmed:abstractText |
Androgens produced by stimulating mouse testis with gonadotropic hormones cause a rise in renal beta-glucuronidase but not an increase in acid or alkaline phosphatase. All subcellular components increase in beta-glucuronidase activity, with a relatively greater increment in particulate enzyme as compared with that free in the cytoplasm (non-sedimentable). A small percentage of recovered beta-glucuronidase, acid phosphatase, and alkaline phosphatase is found in material which rises to the surface during centrifugation in sucrose media (fraction I). The specific activity of beta-glucuronidase and acid phosphatase in this fraction is normally quite high with respect to the homogenate, while that of alkaline phosphatase is not. On the other hand, the fraction I material from androgen-stimulated mice exhibits a further increase in specific activity with respect to beta-glucuronidase and not acid phosphatase. It thus appears that there is an independence in the behavior of individual enzymes in response to physiologic stimuli in spite of obvious morphologic proximity.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/13944005-13270728,
http://linkedlifedata.com/resource/pubmed/commentcorrection/13944005-13367008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/13944005-13654438,
http://linkedlifedata.com/resource/pubmed/commentcorrection/13944005-13694972,
http://linkedlifedata.com/resource/pubmed/commentcorrection/13944005-13942967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/13944005-14907713
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pubmed:keyword | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
OM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0021-9525
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
253-8
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pubmed:dateRevised |
2010-6-22
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pubmed:meshHeading | |
pubmed:year |
1963
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pubmed:articleTitle |
Beta glucuronidase-rich cytoplasmic particles in androgen-stimulated mouse kidney. A cytobiochemical study.
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pubmed:publicationType |
Journal Article
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