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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1992-11-13
|
| pubmed:abstractText |
Seven patients (mean age, 50.7 +/- 20.4 years; range 21-77) with plasma cell granuloma (PCG) of the lung are reported. Cough and sputum were the most common presenting symptoms, followed by fever. Elevated erythrocyte sedimentation rate and serum C-reactive protein levels were found in all patients tested. Radiologically, five cases presented as solitary, well-circumscribed masses and two as ill-defined, pneumonia-like densities. One showed focal calcification. No predilection of occurrence was observed in either lobe of the lung. Histologically, the lesions consisted of a proliferation of mature plasma cells and reticulo-endothelial cells supported by a stroma of granulation tissue, with varying degrees of myxoid change or collagenization. Angioinvasion within the lesion was observed in 4 of the 7 cases. Immunohistochemical staining revealed the IgG-predominant polyclonal nature of the plasma cells, indicating a reactive inflammatory process rather than a neoplastic one. Electron microscopy confirmed the benign nature of the plasma cells with fibroblast and myofibroblast proliferation admixed with that of other inflammatory cells.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0918-2918
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
31
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
756-65
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:1392177-Adult,
pubmed-meshheading:1392177-Aged,
pubmed-meshheading:1392177-Bronchial Diseases,
pubmed-meshheading:1392177-Female,
pubmed-meshheading:1392177-Humans,
pubmed-meshheading:1392177-Immunoglobulin G,
pubmed-meshheading:1392177-Immunohistochemistry,
pubmed-meshheading:1392177-Male,
pubmed-meshheading:1392177-Microscopy, Electron,
pubmed-meshheading:1392177-Middle Aged,
pubmed-meshheading:1392177-Plasma Cell Granuloma, Pulmonary
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Seven patients with plasma cell granuloma (inflammatory pseudotumor) of the lung, including two with intrabronchial growth: an immunohistochemical and electron microscopic study.
|
| pubmed:affiliation |
Pathology Section, Kanazawa University Hospital, School of Medicine, Japan.
|
| pubmed:publicationType |
Journal Article
|