Linked Life Data

1391798

Source:http://linkedlifedata.com/resource/pubmed/id/1391798

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-11-4
pubmed:abstractText
The ability of macrophages to act as accessory cells for the antigen mediated stimulation of T lymphocytes has been unequivocally established in in vitro experiments. However, in vivo experiments are required to investigate whether the in vitro abilities of cells reflect their in vivo function. In order to study whether or not macrophages are required for the induction of antibody production in vivo, a liposome mediated macrophage elimination technique has been developed. Results obtained until now, have confirmed the role of macrophages in the induction of the antibody response against particulate antigens. However, macrophages are not required for the induction of the response against soluble antigens. Contrarily, in various organs they seem to regulate the latter response by suppression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1044-5323
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
237-45
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Macrophages as accessory cells in the in vivo humoral immune response: from processing of particulate antigens to regulation by suppression.
pubmed:affiliation
Department of Cellbiology, Faculty of Medicine, Free University, Amsterdam, The Netherlands.
pubmed:publicationType
Journal Article, Review